Pro-Lab Diagnostics USA offers a comprehensive menu of Pro-Amp™ isothermal nucleic acid amplification panels designed for use in high-complexity, CLIA-certified laboratories. These panels support the rapid, accurate multiplex detection of infectious disease pathogens using proprietary ProAmpHT Isothermal Amplification technology — a cost-effective, high-throughput alternative to conventional PCR.
What is Pro-Amp™?
Pro-Amp™ panels are isothermal NAAT (Nucleic Acid Amplification Test) assays that amplify target genetic material at a constant temperature, eliminating the need for thermal cycling instrumentation. This approach delivers several advantages over traditional PCR:
- Faster time-to-result — amplification completed in 15–60 minutes
- Simplified instrumentation — no thermocycler required
- High sensitivity and specificity equivalent to PCR
- Lower operational complexity for laboratory staff
- Integrated resistance gene detection in a single assay
Available Panel Menu
Pro-Amp™ panels cover the most clinically significant infectious disease categories. Each panel is fully customizable to include the specific targets most relevant to your patient population.
| Panel | Key Targets | Specimen Type |
|---|---|---|
| UTI Panel | 19 basic + 11 extended uropathogens, resistance genes | Urine |
| Wound Infection Panel | 16 basic + 11 extended organisms | Wound swab / tissue |
| Respiratory Panel (RPP) | 18 basic + 24 extended viral/bacterial targets | NP swab / BAL |
| Gastrointestinal (GI) Panel | 12 basic + 8 extended enteric pathogens | Stool |
| Vaginitis Panel | 17 bacterial/fungal targets | Vaginal swab |
| STI Panel | 11 sexually transmitted pathogen targets | Urogenital swab |
| Candidiasis Panel | 7 Candida species | Multiple specimen types |
| C. diff Panel | C. difficile + Toxin A/B | Stool |
| Antibiotic Resistance Panel | Beta-lactam, methicillin, vancomycin resistance genes | Multiple specimen types |
| Nail Fungus Panel | 11 dermatophyte and fungal targets | Nail clipping / scraping |
Resistance Gene Integration
A key differentiator of the Pro-Amp™ platform is the integration of resistance gene profiling directly into standard panels. Rather than requiring separate reflex testing, resistance genes including KPC, NDM, OXA-48, VIM, IMP, mecA, mecC, vanA, and vanB are detected simultaneously with pathogen identification — providing clinicians with actionable antibiotic stewardship data from a single test run.
Clinical Impact
Integrated resistance gene data enables clinicians to de-escalate from empiric broad-spectrum therapy within 24 hours, reducing C. diff risk, improving outcomes, and supporting facility-level antibiotic stewardship programs.
Laboratory Requirements
Pro-Amp™ panels are classified as high-complexity tests under CLIA regulations (42 CFR Part 493). Performing laboratories must hold a CLIA certificate of high complexity and meet applicable personnel and quality system requirements. Pro-Lab Diagnostics provides comprehensive onboarding support, validation documentation, and ongoing technical consultation for implementing laboratories.
Ordering and Distribution
Pro-Amp™ panels are distributed through Thermo Fisher Scientific and Cardinal Health, and are also available directly through Pro-Lab Diagnostics USA. Contact our team to discuss panel customization, volume pricing, and implementation support.
